World Journal of
Pharmaceutical and Life Sciences

BIOSENSORS: AN EMERGING ANALYTICAL TOOL FOR THE EARLY DIAGNOSIS OF CANCER BIOMARKERS TO REDUCE THE MORTALITY RATE

Pankajkumar Yadav*, Rohit Kumar, Nishant Patidar, Sakshi Singh, Sayyad Abdulhakim Abdullah and Manish Mourya

ABSTRACT

Cancer is the serious health problem characterized by the uncontrolled multiplication of cells. It is the second leading cause of mortality throughout the world. Effective and accurate early diagnosis is current need of hour to reduce the severity and mortality rate of cancer. In the past few years, biosensors have gained significant attraction in the detection of the emerging cancer biomarkers. These are the analytical devices that has vast potential to detect the biomolecules like protein, DNA, RNA and converting them into detectable electrical signal. Biosensor technology can be designed to provide reliable and accurate detection of cancer biomarkers, imaging study of cancer cells, and to detect the effectiveness of chemotherapeutic agents at various target sites. However, a major challenge in the development of biosensors is that cancer is highly complex set of diseases. In this review, we highlighted the challenges in the early detection of cancer, emerging use of biosensors as a diagnostic tool, and some future applications of biosensor technology.

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