World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Shaista Firdous* and S. H. Rizwan


Surface Enhanced Raman Spectroscopy is an offshoot of Raman Spectroscopy offering improved characteristics like compound specific Raman fingerprint for the identification of substances, rendering information on chemical and physical characteristics. Further the technique is non-destructive, highly sensitive and has expanded scope in research fields of analytical, bioanalytical, biophysical and life sciences. This review presents the basics of SERS theory, the prevalent Raman principles, and the mechanisms of SERS enhancement. In any SERS application, SERS substrate plays a pivotal role. A brief description of different SERS substrates, their fabrication method has been presented. Lastly, the related enhanced techniques like Tip-enhanced Raman scattering (TERS), Shell-isolated NP-enhanced Raman scattering (SHINERS), etc., have been mentioned.

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