World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

ISOLATION OF AN ISOFLAVONE FROM SUDANESE ACACIA NUBICA STEM BARK AND ANTIMICROBIAL ACTIVITY OF THE ETHANOL EXTRACT

Abdel Karim M.*, Mohamed Y., Faiza I. and Alhafez M.

ABSTRACT

A flavonoid - compound (I)- was isolated from the ethanol extract of Acacia nubica stem bark by thin layer chromatography and its structure was partially characterized on the basis of its spectral data (UV, NMR). The ethanol extract of Acacia nubica was screened for antimicrobial activity against five standard human pathogens : Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeroginosa, Escherichia coli and the fungal species Candida albicans. The ethanolic extract exhibited significant antibacterial and antifungal activity against test organisms.

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