World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

A CASE REPORT ON LINEZOLID INDUCED HYPERSENSITIVITY REACTIONS

*Aiswarya A. A., Jismy Jose, Linsa Linet V. and Adlina Das

ABSTRACT

A 15 year old female patient was infected with abscess on right axilla. It required a surgical management. She was post operationally treated with IV antibiotics (Cefoperazone + Sulbactam) but the wound doesn’t heal. So she was prescribed with linezolid. Linezolid is the first member of the synthetic antimicrobial agent ‘Oxazolidinone’ approved for treatment of complicated and uncomplicated skin and soft tissue infections. In this case soon after administration of first dose of drug prescribed itching, rashes, shortness of breath, angioedema and unconsciousness was observed as a result of hypersensitivity reactions. This condition was managed with Inj. Hydrocortisone and Inj. Avil and suitable supportive measures. Doctors must be careful for the unusual side-effects of this drugs and should take suitable measures to manage it.

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