World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

PREPARATION AND EVALUATION OF OCULAR INSERTS OF FLURBIPROFEN FOR CONTROLLED DRUG DELIVERY

Upadhyay Nikita*, Prajapati Sonu, Chaturvedi Sonam and Pathan Khan Javed

ABSTRACT

The Aim and Objective of the present study is to formulate and evaluate the ocular Inserts of flurbiprofen using different polymers Such as HPMC, Eudragit L100 at various concentrations and combinations using dibutylphthalate as plasticizer. Different formulations were prepared and evaluated for thickness, moisture uptake, weight, Drug content, surface pH.IR spectral analysis showed that there is no interaction of Drug with polymer which indicates the intactness of drug in the formulation. Keywords: flurbiprofen, Hydroxypropymethylcellulose, ocular inserts, Eudragit L100, Dibutylphthalate.

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