World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

EVALUATION OF ANTI-MICROBIAL (IN-VITRO) ACTIVITY OF ARICLEANSE CREAM

*Dr. S. Nipanikar, Dr. S. Agnihotri, Dr. S. Panicker and N. Shelke

ABSTRACT

Ari Healthcare Pvt. Ltd. has developed Aricleanse Cream for treatment of Acne vulgaris, Hyperpigmentation and various skin diseases. The current study was conducted to evaluate anti-microbial potential of Aricleanse Cream in comparison with various formulations (F1-F8), Clindamycin and Doxycycline against Staphylococcus aureus, Staphylococcus epidermidis and Propionibacterium acnes. It was observed that F-1 to F-8 does not show anti-microbial activity against Staphylococcus aureus and Staphylococcus epidermidis. The zone of inhibition of Aricleanse cream was 18 mm against Staphylococcus aureus which is less as compared to Clindamycin (26 mm) and Doxycycline (30 mm). Also, the zone of inhibition of Aricleanse cream was 12 mm against Staphylococcus epidermidis which is less as compared to Clindamycin (26 mm) and Doxycycline (30 mm). Formulations F1, F-2 and Aricleanse cream showed activity against Propionobacterium acnes. Standard drugs Clindamycin and doxycycline failed to show antimicrobial activity against P. acnes. It can be concluded that Aricleanse cream possesses antibacterial activity.

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