World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

BRIEF REVIEW OF LAUHA MARANA W.S.R. TO PHYSIO CHEMICAL CHANGES

*Dr. Mamta Ramgopal Biyani*, Dr. Nalini Ramesh Hedaoo, Dr. Ujwala Ashokrao Jadhao

ABSTRACT

Introduction -Marana is the procedure which purified and detoxified material and converted into easy assimilation, absorbable and adaptable form. Loha bhasma is mineral based Ayurvedic medicine. It contains elemental iron microfine particle prepared through the process of calcination under high temperature. Marana brings many physio chemical changes like reduction in particle size to gain biological benefit. Aims and Objectives- To do detailed study on Lauha Marana,To Evaluate chemical changes during Marana procedure in lauha bhasma Discussion - Lauha should not be taken less than 5 Pala and more than 13 Pala for processing. Kant lauha and Tikshna lauha is considered as best raw material for lauha bhasma preparation. Lauha marana or incineration process mostly follow Trividha paka method that are Bhanupaka, Sthalipaka and Putapaka. Triphala contains ascorbic acid which increases the bioavailability of Iron by converting Fe3+ to Fe2+. Repetition in heating and cooling just like in samanya and vishesh shodhana causes disruption in compression tension equilibrium and leads to increased brittleness, reduction in hardness, and finally reduction in the particle size. During Bhanupaka the ultraviolet radiation present in the sunlight reduces the oxidation state of Fe in the presence of Vitamin C present in the Triphala decoction thereby improving the bioavailability. Conclusion- Lauha bhasma is a mixture of ferrous oxide, Ferrous Sulphide, Ferric Oxide and other trace element.

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