World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

MULTIDRUG-RESISTANCE ACINETOBACTER BAUMANNII PNEUMONIA IN A MEDICAL STABLE DIALYSIS PATIENT, DAR-ES-SALAAM TANZANIA: A CASE REPORT

Sima Rugarabamu*, Fatuma Maliki, Iddy Shaban, Sebastian Komba, Humphrey Kimonge, Eliya Emmanuel, Gloria Golani, Victoria Ndomba and Loyce Kaunga

ABSTRACT

Background: Bloodstream infection caused by multidrug –resistance Acinobacter baumanii (MDRAB) has become a major clinical concern. Patients with chronic kidney disease, particularly those with end-stage renal disease who require dialysis and/or kidney transplantation, have some of the highest rates of colonization and infection with antimicrobial resistance worldwide. Antimicrobial resistance limits treatment options and increases the risk of infection-related morbidity and mortality. The requirement to use alternative antibiotics is concern regarding the emergence of isolate resistance in Chronic Kidney disease (CKD) patients. This highlights the dire need for new treatment options as well as consistent implementation and improvement of basic infection prevention practices. Clinicians involved in the care of patients with renal disease must be familiar with the local epidemiology of antibiotic resistance, remain vigilant for the emergence of novel resistance patterns and adhere strictly to practices proven to prevent transmission of antibiotic resistance microbes and other pathogens. Case Presentation: This report multidrug –resistance Acinobacter baumanii (MDRAB) isolated from blood sample of a 74-year-old female who is permanently catheterized undergoing dialysis treatment at hospital in Dar-es-salaam, Tanzania. Conclusions: We have isolated a multidrug resistance A. baumannii in a medical stable dialysis patient diagnosed with pneumonia. Health care associated infections of MDR A.baumanii are critical problem in these patients; therefore, urgent focused intervention to contain the spread of MDR nosocomial infection is needed. Treatment of dialysis patient should be guided by antimicrobial susceptibility testing.

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