FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF OXCARBAZEPINE USING DIFFERENT POLYMERS
The aim of present investigation was to formulate and evaluate the sustained release tablets of Oxcarbazepine. These matrix tablets were prepared by direct compression method using natural polymers like Aloes Powder,Gum copal, Gum dammar. In vitro drug release studies were performed by USP dissolution apparatus type II using 0.1N HCL buffer and 6.8 Phosphate buffer for 12hrs. Among all the 12 formulations Formulation F9 showed maximum drug release 99.53% for 12hrs study. It was observed from the kinetic studies that all the formulation followed Peppas-Release kinetics.[Full Text Article] [Download Certificate]
NEWS & UPDATION
BEST PAPER AWARDS
World Journal of Pharmaceutical and life sciences Will give best paper award in every issue in the from of money along with certificate to promote research .
Best Article of current issue
Download Article : Click here