World Journal of
Pharmaceutical and Life Sciences

EFFECT OF PHYTOESTROGEN (FLAX SEEDS) ON PERIMENOPAUSAL & MENOPAUSAL SYMPTOMS IN FEMALES RESIDING IN FARIDABAD

V. Thorat*, D. Sanghi and A. Sharma

ABSTRACT

The term “Menopause symptoms” can describe any of the changes a woman goes through either just before or after menstruation cessation due to the lack of estrogen hormone. Phytoestrogens are plant-derived compounds that structurally or functionally mimic mammalian estrogen and available in flax seeds in good amount. Present study was conducted to assess the effect of phytoestrogen (Flax seeds) on menopausal symptoms. Total 40 subjects were recruited and were equally divided in to two group- Group 1(flax seeds-20 gms) and Group 2(placebo). Baseline data was collected using pretested questionnaire, which comprised demographic, anthropometric, medical and dietary profile. Menopausal symptoms severity was recorded using Heinmann’s menopausal rating scale (MRS) at baseline and at last follow-up (30-days). At base line, both the groups were comparable. Hot flushes, heart discomfort, sleeping disorder, urinary complaints, depression and physical-mental exhaustion symptoms severity get reduced after intervention of flax seeds. So the present study concluded that flax seeds might be beneficial for some menopausal symptoms. But the present findings warrant confirmation by doing longitudinal studies on larger number of samples.

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