World Journal of
Pharmaceutical and Life Sciences

DETECTION OF CORONARY ARTERY DISEASE USING 2D- REGIONAL (SEGMENTAL) LONGITUDINAL STRAIN (RLS) COMPARED WITH CORONARY ANGIOGRAPHY IN PATIENT WITH ACUTE CORONARY SYNDROME

Dr. Ghazi Farhan Haji, *Imad Mahmood Hussein, Dr. Wajih Qasim Taha

ABSTRACT

Speckle-tracking echocardiography is a new noninvasive ultrasound imaging technique that allows for evaluation of global and regional myocardial function. Our study aimed to evaluate the accuracy of regional (segmental) longitudinal strain by 2D - STE for pick up culprit vessels in acute coronary syndrome (ACS) by detecting ischemic segments of the corresponding territories and its severity compared with coronary angiography as a gold standard, in patients with acute coronary syndrome. This cross sectional study was performed in Baghdad teaching hospital / Iraq during the period from March 2017 to March 2018 on (50) patients with (ACS) who underwent 2-dimensional speckle tracking echocardiography (2D-STE) for left ventricular regional longitudinal strain (RLS) immediately before invasive coronary angiography. Results showed that the mean age of patients was 57.2 (+ 7.9) years, regional longitudinal strain-speckle tracking showed that 38 patients had coronary artery disease (CAD) and 12 patients had no CAD, versus coronary angiography which showed that 29 patients had CAD, while 21 patient had no CAD or non significant lesions. The validity of RLS according to coronary angiography showed 100% sensitivity, 57.1% specificity, 76.3% positive predictive value (PPV), 100% negative predictive value (NPV) and 82% accuracy. It can be concluded from the current study that (RLS) Speckle-tracking echocardiography technique has high sensitivity but with relatively low specificity in diagnosis of coronary artery disease in patients with acute coronary syndrome.

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