World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), Web of Science Group (Under Process), Directory of Research Journals Indexing, 

Abstract

A SYSTEMIC REVIEW ON ADVERSE DRUG REACTIONS REPORTED IN A PERIOD FROM 2014 TO 2018 IN DIFFERENT PARTS OF INDIA

Sravanthi Appikonda*, Lavanya Eli, Dhanush Bellapu and Padmalatha Kantamneni

ABSTRACT

One of the main causes for the morbidity and the mortality in the world is Adverse Drug Reaction(s) [ADR]. Thalidomide tragedy is the best example for ADR after which international attention to patient safety was gradually increased. There was global occurrence of 10% of ADRs where 2% were reported in India. Major contributors for morbidity, mortality and hospitalization of patients and increasing economic burden of patients are ADRs. CDSCO and Pharmacovigilance play a key role in the identification of ADRS. This study was carried out by collecting different ADRs collected and reported by health care professionals at different places of India. Underreporting was the main problem in reporting an ADR which can be overcome by following spontaneous reporting system. Most vulnerable organs for ADRs are Gastrointestinal tract along with skin & appendages. Antimicrobials are the class of drugs which majorly causes ADRs. Adults and middle aged are common group of people affected due to ADRs. Causality, severity and preventability were calculated using different scales like WHO-UMC causality assessment scale, Naranjo causality assessment scale, Hartwig’s severity assessment scale and Schumock and Thornton Preventability assessment scale.

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