World Journal of
Pharmaceutical and Life Sciences

CRACKING HOMO SAPIEN SKIN PIGMENTARY ORDER, AETIOLOGY OF SKIN DEPIGMENTARY DISORDER AND ITS ATTENDANT SKIN CANCER OR CANCER AND THEIR REHABILITATION WITH NAPHTHOQUINONE THERAPY

Dr. S. S. Sawhney*

ABSTRACT

Introduction: The black Homo sapien prototype at tropics, relevant to earthly conditions, had been evolved under the sapient biostrategy of natural selection, but with a code. The skin depigmentary disorder among non- European black Asian, African and Australian at tropics, and the assumption of light- toned integumental coat by white European at beyond tropics are the evolutionary defiances. The aim of this study is to unravel and crack the mechanisms thereof, and rehabilitate the skin depigmentary disorder among the Homo sapiens. Methods and material: Fourteen Asian Indian consented and volunteered for this study. Complete Body Scan Analysis was conducted on nine volunteers. Four HES patients were treated topically or orally or both with vitamin K1 or naphthoquinone precursors to vitamin K2 (Plumbago Zeylanica L.), followed by exposure of relentless sun high intensity UVB. A normal female volunteer was put on the dose of 10g of Walnut Karnels of Juglons regia L. for a year in addition to her staple diet, followed by exposure of relentless sun high intensity UVB. Results: The interplay of the epidermal vitamin K threshold and the relentless sun high intensity UVB has been identified as the mainstay of the skin pigmentary order as defined in black Homo sapien prototype at tropics. The vitamin K deficiency in Homo sapiens has been identified as the skin depigmentary disorder precipitant, whereas the relenting sun low intensity UVB precipitates light – toned integumental coat among the Homo sapiens at beyond tropics. These evolutionary defiances among Homo sapiens result in the maximization of their vulnerability to skin cancer or cancer. The vitamin K based Naphthoquinone Therapy offers new options for the treatment, prevention and pre- emption of skin depigmentray disorder or cancer. Conclusion: The vitamin K has been identified as the pro skin pigmentary order, anti-skin depigmentary disorder and anti-cancer vitamer. The supplementation of staple diet with plant -based highly photosensitive and UVB- harvesting 1, 4-naphthoquinone derivatives: root powder of Plumbago zeylanica L and fruits of Juglona regia L, is strongly recommended to keep skin depigmentary disorder and cancer at bay.

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