World Journal of
Pharmaceutical and Life Sciences

BIOGENIC AND DRUG CAPPED AuNps. AND THEIR BIOMEDICAL APPLICATION

Dr. Bharat A. Makwana*, Jagruti P. Vala, Pooja R. Popat, Pooja S. Thakur and Viral A. Patel

ABSTRACT

Development of green nano technology is generating interest of researchers toward eco friendly, safe, non-toxic, eco-friendly route of synthesis which can be used for the manufacture at a large scale. This is a simple, cost-effective, stable for long time and reproducible aqueous room temperature synthesis method to obtain a self-assembly of Au and Pd nanoparticles with the leaf extract of Hibiscus rosa. In the present study, we report the bio synthesis of aqueous stable gold and palladium nanoparticles by using petal extract of Hibiscus rosa as both reducing and capping agents.I have also synthesiszed Gold nanoparticle with the use of isonazide drug as redusing agents and PEG (poly Ethylene Glycol) as capping agents. The synthesized nanoparticles were characterized by UV/Vis, particle size analyzer (PSA) and transmission electron microscopy (TEM). We discuss here a quick, simple, economic, and eco friendly method through a completely green route for the selective detection. Furthermore this nanoparticles have applied in biological system like, gold nano particles for selective sensing of amino acid (L- dopa) potential antimicrobial agent and AuNps. nanoparticles applied for the catalyst study.

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