World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

SYNTHESIS OF SOME COUMARIN-ETHYLIDENEAMINO-2-THIOXOIMIDAZOLIN-4-ONE DERIVATIVES

Ali Mahdi* and Yasameen K. Al-Majedy

ABSTRACT

The synthesis of some coumarin derivatives was aimed at creating a new molecular frame work. Seven of coumarin derivatives have been synthesized by reacting of 3-acetyl-2H-chromen-2-one with thiosemicarbazide followed by cyclization with ethyl chloroacetate then reacted with acetic anhydride, 4-chlorobenzaldehyde and diethylamine to yield other compounds All these compounds were characterized by physical and spectral data.

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