World Journal of
Pharmaceutical and Life Sciences

MAGNETIC MICROSPHERE-A NOVEL APPROACH IN TARGETED DRUG DELIVERY SYSTEM

Dr. Radhika Parasuram Rajam*, Keerthana Giriraj, Monashilpa Palanivel and Poovitha Selvaraj

ABSTRACT

Recently a number of novel drug delivery systems have emerged with various routes of administration, minimize the drug degradation, to prevent side effects, desired drug concentration and to achieve controlled and targeted Drug delivery. Magnetic microspheres hold great promise in reaching the goal of controlled and site specific drug delivery. The magnetic properties of these particles add a new dimension upon application on an external magnetic field. Magnetic microspheres are supra molecular particles that are small enough to circulate through capillaries without producing embolic occlusion (<4micrometer). Magnetically targeted drug delivery by particulate carriers is an efficient method of delivering drugs to localized sites such as tumors. High concentration of chemotherapeutic or radiological agents can be achieved near the target site, without any toxic effects to normal surrounding tissues. These are various methods used to prepare magnetic microspheres along with different evaluation parameters. The review entails the current application of magnetic microspheres, as well as future prospects and problems to be overcome for the efficient and beneficial use of the magnetic microspheres.

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