World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

SYNTHESIS AND CHARACTERIZATION OF NEW CHALCONE COMPOUNDS DERIVED FROM QUINOLINE.

Hiba H. Ibraheem* and Sarah Abdulhamza Hameed

ABSTRACT

Three chalcones (4'-amino-4-methoxy chalcone, 4'-amino-3,4-dimethoxy chalcone and 4'-amino-3,4,5-trimethoxy chalcone) has been synthesized by reaction of ketone (compound (3)) with appropriate aromatic aldehydes ( 4-hydroxy-3-methoxybenzaldehyde ,4-N,N-dimethylaminobenzaldehyde and 2-hydroxybenzaldehyde) in presence of Potassium hydroxide to obtain chalcone derivatives (4a-c). The new synthesized compounds have been characterized using Melting point, TLC, FT-IR spectroscopy and 1H-NMR.

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