World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), Web of Science Group (Under Process), Directory of Research Journals Indexing, 

Abstract

AN ASSAY METHOD FOR SIMULTANEOUS ESTIMATION OF AMLODIPINE AND BENAZEPRIL IN ITS BULK AND PHARMACEUTICAL DOSAGE FORM BY RP-HPLC METHOD

Fatima Mazher* and Dr. R. Vani

ABSTRACT

A short selective, precise, accurate and sensitive for the estimation of Benazepril and Amlodipine was done by RP-HPLC. The assay of Benazepril and Amlodipine was performed with tablets and the % assay was found to be 100.08 and 100.66 which shows that the method is useful for routine analysis. The linearity of Benazepril and Amlodipine was found to be linear with a correlation coefficient of 0.999 and 0.999, which shows that the method is capable of producing good sensitivity. The acceptance criteria of precision is RSD should be not more than 2.0% and the method show precision 0.8 and 0.9 for Benazepril and Amlodipine which shows that the method is precise. The acceptance criteria of intermediate precision is RSD should be not more than 2.0% and the method show precision 0.5 and 0.7 for Benazepril and Amlodipine which shows that the method is repeatable when performed in different days also.

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