World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), Web of Science Group (Under Process), Directory of Research Journals Indexing, 

Abstract

A NEW SEPARATION TECHNIQUE FOR METHOD DEVELOPMENT AND VALIDATION OF ALOGLIPTIN AND PIOGLITAZONE IN ITS PURE AND PHARMACEUTICAL DOSAGE FORM BY RP-HPLC METHOD

Hameeda Begum*, Dr. R. Vani and Dr. D. Rama Krishna

ABSTRACT

A short selective, precise, accurate and sensitive for the estimation of Alogliptin and Pioglitazone was done by RP-HPLC. The estimation of Alogliptin and Pioglitazone was done by RP-HPLC. The assay of Alogliptin and Pioglitazone was performed with tablets and the % assay was found to be 99.93 and 99.95 which shows that the method is useful for routine analysis. The linearity of Alogliptin and Pioglitazone was found to be linear with a correlation coefficient of 0.999 and 0.999, which shows that the method is capable of producing good sensitivity. The acceptance criteria of precision is RSD should be not more than 2.0% and the method show precision 0.6 and 0.8 for Alogliptin and Pioglitazone which shows that the method is precise. The acceptance criteria of intermediate precision is RSD should be not more than 2.0% and the method show precision 0.6 and 0.6 for Alogliptin and Pioglitazone which shows that the method is repeatable when performed in different days also.

[Full Text Article]

BEST PAPER AWARDS

World Journal of Pharmaceutical and life sciences Will give best paper award in every issue in the from of money along with certificate to promote research .

Best Article of current issue

Download Article : Click here