World Journal of
Pharmaceutical and Life Sciences

CONSTITUENTS OF SUDANESE ZIZIPHUS JUJUBE MILL. OIL AND ANTIMICROBIAL ACTIVITY OF THE OIL

Dr. Abdel Karim M.*, Samir A. and Mahmoud M. A.

ABSTRACT

Ziziphus jujube is used traditionally against rectal and intestinal ulcers. The plant is considered as a natural remedy for liver diseases. In this study Ziziphus jujube seed oil was analyzed by GC-MS. The analysis revealed the presence of 30 components. The fatty acids constituted 51.89% of the oil; alcohols constituted 47.20%, the rest are hydrocarbon, ketones, vitamin E and a phenol. The following major constituents have been detected by GC-MS analysis: i)-cis-13-eicosenoic acid methyl ester(28.40%) ; (ii)-9-octadecen-1-ol(Z)-(21.56%).; (iii)- 9-octadecen-1-ol(E)-(20.27%) and (iv)-13-docosenoic acid methyl ester(10.83%). In the well diffusion bioassay The oil showed significant activity against Bacillus subtilis, Pseudomonas aeroginosa and the yeast Candida albicans. It also exhibited weak activity against Staphylococcus aureus. However, the oil did not show any inhibitory effect against Escherichia coli.

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