World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

TOXIC EFFECT OF FLUORIDE ON TOTAL PROTEIN, HDL, LDL AND VLDL OF RAT

Dipali D. Pillewar*, Smita B. Patil, Bhavana S. Pillai and S. S. Pawar

ABSTRACT

Fluoride is a widespread non biodegradable and relatively persistent pollutant, which at low levels of contamination causes serious health problems difficult to cure. In the present study the effects of sodium fluoride induced toxicity in rat liver was evaluated. Twenty rats were divided into four experimental groups containing 5 rats each. 1st group was used for control and 2nd, 3rd and 4th groups were ingested with different concentration of fluoride water respectively for 56 days. The data indicate significant reduction in total protein and HDL in experimental animals while LDL and VLDL were highly elevated in the exposed rats.

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