World Journal of
Pharmaceutical and Life Sciences

EVALUATION OF PHYTOCHEMICAL ANALYSIS OF ANDROGRAPHIS PANICULATA LEAF AND STEM EXTRACT

Jyoti Pandey, Vimal K. Saini and Wasim Raja*

ABSTRACT

The present study is the continuation of a program aimed at investigation of photochemical properties of Andrographis paniculata leaf and stem extract to justify the traditional claim endowed upon this herbal drug as a rasayana in Ayurveda. Andrographis paniculata is a member of the family Acanthaceae. It is commonly known as kalmegh, bhumineeb, chirayata. It is a valuable traditional medicinal plant. It has antibacterial, antioxidant, antidiabetic, antipyretic, hepatoprotective cardiovascular and anti-virus including inhibited HIV properties. The plant commonly used by the local people, for the treatment of common cold, fever, Malaria, liver diseases, snakebite diabetes, and some skin infection. Phytochemical screening of the methanol, petroleum ether, acetone and chloroform extract of leaves and stem bark of Andrographis paniculata Linn showed the presence of glycosides, phytosterol, saponins, tannins, flavonoids and terpenoids in all extractions fragments. The presence of terpenoids as major constituents of the plant leaves as well as stem bark extract that are commonly known to posses different activity. These results support the traditional use of the plant in therapy of different disease.

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