World Journal of
Pharmaceutical and Life Sciences

DRUG UTILISATION IN THE MANAGEMENT OF HYPERTENSION IN A TERTIARY CARE HOSPITAL

Shahana Begum*, Dr. J. Raghuram and Sumaiya Fatima

ABSTRACT

Aim: The Present aim is to assess the for drug utilisation in the management of hypertension at Aster Prime Hospital (Hyderabad). Methodology: The observational study is undertaken in drug utilisation in the management of hypertension indoor patient department in a tertiary hospital for a period of eight months for auditing of prescriptions and drug utilisation, during which data of 180 patients was collected. The study included all patients prescribed with antihypertensive drugs across all departments during the study period. Results: In our study we conclude that number of patients receiving: ? Monotherapy of antihypertensive drugs, Amlodipine was the most commonly used drug which was prescribed for 89 (49.44%) patients were found to be most rational and Galantamine was found to be semi rational. ? Number of patients receiving two drug combination therapy of antihypertensive drugs 36 (20%) patients. Amlodipine + atenolol was most commonly prescribed two drug combination which was prescribed for 7 patients (3.88%). ? Number of patients receiving three drug therapy of antihypertensive drugs out of 180 prescriptions three drugs were prescribed for 20 (11.11%) patients. In that losartan + hydrochlorothiazide + amlodipine and Enalapril + Amlodipine + Hydrochlorothiazide were the most commonly prescribed three drug combinations prescribed. ? The four drug combinations were the least prescribed. Four drugs were prescribed only for 8 (4.44%) patients. Hydrochlorothiazide + Telmisartan + Amlodipine + Atenolol and Telmisartan + Hydrochlorothiazide + Metoprolol + Amlodipine were the two four drug combinations prescribed for 8 patients.

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