World Journal of
Pharmaceutical and Life Sciences

A SINGLE BLIND CONTROLLED STUDY OF CHATURBEEJ CAPLET AND DICLOFENAC SUPPOSITORY IN POST-OPERATIVE PAIN MANAGEMENT

*Dr. Mangesh Kachruji Bharadkar and Dr. Rashmi Anil Kale

ABSTRACT

Pain is a more terrible lord of mankind than even death himself - Albert Schweitzer God has bestowed mankind with the best of his gifts and made him the supreme most creature of the universe. Health is one such precious possession, wisdom and art. Strength and wealth are of no use if health is lacking. Thus it is the prime aim of Ayurveda and the one, all physician and surgeon should try for, i.e. protecting the health of the health and restoring health for the diseased. The post-operative pain management is special area where doctors has to deal with great patience particularly lower abdominal and in pelvic surgeries, ano rectal surgeries. Surgeries under spinal and epidural anesthesia has analgesic effect for hours after procedure. There are Paracetmol and Diclofenac suppository are available and working moderately. These drugs are having adverse effect like rectal bleeding, rectal ulceration etc. Rectal administration provides rapid absorption of many drug and easy alternative to IM/IV route. It is painless procedure. The most important consideration are slow onset of disintegration (minutes), absorption of medicine and the prolonged duration of effect(analgesia) in rectal route. Aim: To study the efficacy of Chaturbeej caplet and Diclofenac suppositories in post-operative pain management. Objectives 1. To study the literature of pain and its management through rectal route.2. To evaluate the efficacy of Chaturbeej caplet in post-operative patients as an rectal analgesic drug. 3. To compare the efficacy of Chaturbeej caplet with Diclofenac suppository. 4. To study the adverse effect of drug like ano-rectitis, rectal ulceration and necrosis. Ayurveda has many drugs and formulations as vedanashamak activity. Following formulation from Bhavprakash is indicated as oral analgesic.[9] This study was carried out to find out one more option for analgesic suppository of natural origin for post operative pain management, this drug administered by Rectal route.

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