World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Scientific Indexing Services (SIS), Indian citation Index (ICI), Directory of Research Journals Indexing, Scintific journal impact factorScientific Journal Impact Factor (SJIF), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Cosmos Impact Factor, IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), Web of Science Group (Under Process), Research Bible, Fuchu, Tokyo. JAPAN, Scholar Article Journal Index (SAJI), Scope Database, Academia, 

Abstract

ANTIULCEROGENIC AND ANTIOXIDATIVE EFFECTS OF AQUEOUS EXTRACT OF CHROMOLAENA ODORATA L. (KING AND ROBINSON)

Elion Itou R. D. G.*, Mayela Nkouka S. H. J., Gouollaly Tsiba, Kiéssé D. S., Etou Ossibi A.W. and Abena A. A.

ABSTRACT

This study aimed to evaluate the antiulcer and antioxidative effects of aqueous extract of C.odorata. The antiulcer effect was evaluated in the mice and rat by using HCl/ethanol mixture, ethanol (EtOH) and the indometacin like ulcerogenic agents. The antioxidative effect was evaluated by spectrophotometer by using the technique of reduction of 1,1-Diphenyl-2-picryl hydrazyl (DPPH) radical. The results obtained show that the aqueous extract (400 and 800 mg/kg) protects the gastric mucosa of experiment animals against the ulcers induced by the ulcerogenic agents. However, no effect was observed on the gastric pH. This action could pass by the increasing gastric mucosa production and not by an inhibition of acid secretion. Moreover, the aqueous extract presents an anti-oxidative effect by reduction of DPPH radical.

[Full Text Article]   [Download Certificate]

WJPLS CITATION

  All Since 2019
 Citation  422  322
 h-index  9  7
 i10-index  4  2

SJIF Impact Factor 6.12  

INDEXING

Indexing

NEWS & UPDATION

    A PHP Error was encountered

    Severity: Notice

    Message: Undefined variable: news

    Filename: views/right_panel.php

    Line Number: 79

    A PHP Error was encountered

    Severity: Warning

    Message: Invalid argument supplied for foreach()

    Filename: views/right_panel.php

    Line Number: 79

BEST ARTICLE AWARDS

World Journal of Pharmaceutical and life sciences is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.

Best Article of current issue

Download Article : Click here

Downloads

  Covering Letter

  Copy Right Form

  Author Instruction

read more

Powered By WJPLS ! All Rights Reserved.

WJPLS

Follow us on: