World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

EVALUATION HAEMATOLOGICAL PARAMETERS OF POLYHERBAL PREPARATION ON STREPTOZOTOCIN INDUCED DIABETIC RATS

Somanathan S. S.*, Ranganayakulu D. and Jayaveera K. N.

ABSTRACT

Objective: The current sudy was designed to evaluate the anti-diabetic and haematological parameters of combined poly herbal extract preparaion on streptozotocin (60mg/kg bw) induced diabetic rats. Asistasia gangetica leaf extract (AGLE-50mg/kg), Ficus racemosa leaf extract (FRLE-75mg/kg) and Morus indica leaf extract (MILE-75mg/kg) were combinely (poly herbal preparation-PHP) administered to diabetic and non diabetic rats. In this study Glibenclamide (5mg/kg) is used as standard drug.[2,3,5] The physiological animal body weight (BW), haematological parameters like Fasting blood glucose (FBG), Oral Glucose Tollarance Test(OGTT), RBC counts (RBCc), WBC counts (WBCc), Haemoglobin level (Hb), Glycocylated Haemoglobin (HbA1C), bleeding time (Bt-duke method), cloting time (Ct-capillary glass method), were studied were studied.[13]

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