World Journal of
Pharmaceutical and Life Sciences

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An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

KAMPILLAKA (MALLOTUS PHILLIPENSIS): A WONDER DRUG IN AYURVEDA- A REVIEW

Dr. Sonali Bihana* and Dr. Shweta Dewan

ABSTRACT

Introduction: Kampillaka (Mallotus philippensis Muell Arg) is the native of North West region. Kampillaka is one of the herbs mentioned in all ancient scriptures of Ayurveda. It has various synonyms like ranjana (colouring agent), recanaka (purgative), raktacurnaka (red powder), karkasa (rough) etc. It was used as a medicine from Vedic period as Takma Nashan. It is observed that the drug is used in 44 formulations, indicated in more than 20 disease conditions including krimiroga (worm infestation), twacha roga (skin disease),vibandha, gulma, vruna, shleshmodara, arsha, shula, jwara, prameha etc. Useful part of the plant is phalaraja and it should be administered internally after passing through shodhana procedures. It is used in various dosage forms such as churna, vati, varti, kalka, taila, ghruta, and malahara. Kampillaka, as one of the audbhida dravya, can be traced since samhita period for its use in virechana. In higher doses kampillaka is found to produces nausea, purging and severe spasmodic pain. . In ancient times, its leaves were used in yagya and its wood was used to make wooden mixer Acetylaleuritolic acid,Coroglaucigenin, Sitosterol, Octacosanol,? –Sitosterol, glycoside, Isorotrlerin. Materials and methods: The concerned classics were explored and the subject matter was compiled and analyzed. Discussion: Fruit and bark of plant contain condensed tannins responsible for antioxidant activity. Some novel chalcone derivatives, mallotophilippens C, D, and E, were isolated from the fruits of M. philippinensis. Mallotoxin or rottlerin has great anticancerous potential. Among the ever-anticancer agents, rottlerin appears to have great potentiality for being used in chemotherapy. Conclusion: The great potential of Mallotus philippinensis cannot be overlooked. There are many medical fields like cancer department where with help of this wonder drug more advances can be expected and the contribution of Ayurveda in the global health segment can be recognized.

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