World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Kolawole Jacob A,* Smith Keturah and Atibli Godwin


Medicines are necessities to every patient, therefore whenever the need arise, the patient have little option but to obtain whatever is available and affordable. The study was aimed at assessing the rationale for medicines substitution and to determine the level of compliance of pharmacists in Jos University Teaching Hospital (JUTH), to WHO principles on interchangeability of medicines. Metformin Hydrochloride was used as a surrogate product. The study was carried out in two phases, with the first phase involving the use self-completion structured questionnaires administered to the pharmacists in the hospital. A total of 63 pharmacists (47males and 16 females) participated in the study. 36.7% affirmed that their selection of generic medicines depends on quality and safety, while 82.53% of the respondent considered cost and 96.8% considered availability a priority. 68% used bioequivalence data if available and 44.2% of the respondent based selection on product popularity, local demands and company’s reputation. Finally, 63.5% based their substitution on patients consent or demand. The pharmacists showed excellent level of compliance to WHO policy on interchangeability and pharmaceutical care principles.

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