World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Senthil Manikandan TJ., Naufal Rizwan TA., Mariraj I., Kannan R.,* Gowri Shankar A. and Narasimhalu CRV.


Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions to drugs characterized by extensive detachment of the epidermis and erosions of the mucous membranes. Here we report a case of Stevens Johnson syndrome with toxic epidermal necrolysis overlap. This case report is to highlight the importance of early diagnosis and necessity for continued avoidance of the inciting drug. In our patient the lesions recurred when the inciting drug was reinstated into the prescription inadvertently. The recurrent lesions were very similar to the initial episode and the patient responded very well to intravenous immunoglobulins and steroid combination therapy during both episodes.

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