World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), Web of Science Group (Under Process), Directory of Research Journals Indexing, Scholar Article Journal Index (SAJI), International Scientific Indexing ( ISI ), Scope Database, 



Suresh Kumar* and Nitin Khatri


Alzheimer’s disease (AD), which is considered to be most common form of dementia leads to neurodegeneration of primarily the cholinergic neurons. The currently available medication based on cholinesterase inhibiting activity can only provide symptomatic relief to the patients undergoing treatment. The present study evaluates the anti-oxidant and anti-butyrylcholinesterase activity of an aqueous extract of Morus nigra. Our findings demonstrated that an aqueous extract of Morus nigra’s fruit significantly inhibited butyrylcholiesterase enzyme and showed maximum inhibition of
54.28±0.33% at the final concentration of 200μg/ml with IC50 value of 126.80μg calculated using the percentage inhibition plot. An aqueous extract of Morus nigra also possessed significant antioxidant activity of 2511.593±0.123 μmol Fe2+ E/g of dried sample and 0.89±0.0005 mmol Trolox E/g of dried sample assessed by Ferric reducing activity of plasma assay and Trolox equivalent antioxidant capacity assay respectively. It is concluded that this plant has potential for alleviating the symptoms associated with AD.

[Full Text Article]


World Journal of Pharmaceutical and life sciences Will give best paper award in every issue in the from of money along with certificate to promote research .

Best Article of current issue

Download Article : Click here