World Journal of
Pharmaceutical and Life Sciences

DEVELOPMENT OF METHODS FOR QUALITY CONTROL OF DRY EXTRACT OF LEAVES AND ROOTS OF VOAD

*Tillaeva G.U. and Khakimzhanova Sh.O.

ABSTRACT

Methods have been developed for the identification and quantitative determination of the active ingredients in dry extracts of the leaves and roots of Woad. Based on the studies carried out, a TLC technique was proposed for authenticity, and a choice of solvents, elution conditions and developers for identifying flavonoids was made. Validation characteristics for determining the sensitivity and detection limit of the prepared drugs are presented, proving the correctness, suitability, reproducibility and specificity of the developed method. To determine the quantitative content of active substances from the dry extract of leaves and roots of usma, a spectrophotometric method was used. The determination was carried out based on flavonoids in terms of luteolin as the dominant element contained in the extracts. The developed conditions will be included in the regulatory document for dry extract of leaves and roots of Woad.

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