World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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*I. U. Sheikh and I. A. Baba


Chickens like other animals depend on various feed resources for the fulfilment of their vitamin requirement. Chickens are much more susceptible to deficiency diseases specially vitamin deficiencies than other animals. Chicken being the monogastric animal, the gut flora of chicken does not synthesis any vitamins rather compete with host for dietary vitamins. More over higher metabolic rate of chicken also needs higher amounts of vitamins to perform vital metabolic reactions in the body. The requirement of vitaminB2 for grower chick is is about 2mg/kg of diet (Singh et al., 1995). Riboflavin is acritical vitamin in the diet of breeder hens for production of hatching eggs. Curled toe paralysis in chicken is associated with riboflavin (vitamin B2) deficiencies. Riboflavin deficiency in chicken severely affects the tissues of the epithelium and myelin sheaths of the main nerve trunks especially in the sciatic nerve. In growing chickens? degenerative changes in the sciatic nerve produce characteristic diseases/symptoms commonly known as „curled toe? paralysis. It is one of the most characteristic signs associated with the vitamin deficiency, resulting in the curling of the chicks toes. The condition nervous system related due to peripheral nerve damage, related to degeneration of the sciatic nerves (the nerves along the back of the chick's leg to the foot). The damage can be reversed if treated quickly, however in longstanding cases where treatment is delayed the condition will become permanent. Although curled-toe paralysis is seen commonly in newly hatched chicks, studies have shown that only about 10% of riboflavin-deficient chicks develop clinical signs.

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