World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Prashanti L. P.*, Sheshashaye and Shailaja S. V.


Gallstones are formed from the constituents of the bile (viz. cholesterol, bile pigments and calcium salts) along with other organic components. They are formed in the gallbladder, but sometimes may develop within extra hepatic biliary passages, and rarely in the larger intrahepatic bile duct. Gallstone disease caused by cholesterol is a frequent clinical illness impacted by hereditary factors, advancing age, female gender, and metabolic factors. The details of „Cholelithiasis? is not mentioned in Ayurvedic classics directly, but the term Pittashaya ashmari can be coined for it, as Vagbhata while explaining the Samprapti of ashmari says that Ashmari is formed in Basti as Rochana is formed in Pittashaya of cow. So the Ashmari formed in Pittashaya of humans, similar to Gorachana can be considered as Pittashaya ashmari. Sushruta explained Pittashaya as one of the Sapta Ashayas in Shareerastana which actively participate in digestion. Gallstones happens when excess Kapha dosha combines with the Pitta characteristics of the viscous fluid bile, causing it to become dry and hardened. Based on the involvement of doshas chikitsa can be given according to the yukti. This always causes symptoms such as "Alasya"or lethargy, "Gaurava" or abdominal heaviness, and “Mandagni”. After analysing the Ayurvedic texts, it was found that due to the similarity in location and function, the bile secreted from the gall bladder can be correlated with the Accha Pitta described in Ayurveda. Owing to the irregular shape of Kapha during the course of digestion and its vitiation owing to Vata and Pitta, the pathogenesis of gall stone disease takes place.

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