World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

ANTIULCER ACTIVITY OF NUTS OF SEMECARPUS ANACARDIUM LINN.

Dr. R. Xavier Arulappa*, M. Jerubin Welsingh, V. Vasudevan and S. Mohan

ABSTRACT

This study was performed to determine the antiulcer activity of extracts of semecarpus anacardium against pylorous ligation induced gastric ulcer. The ethanolic extract of semecarpus anacardium at the dose of 400 mg/kg P.W markedly decrease the incidence of ulcers in pyloric ligated rats. In pyloric ligated rats, there was an increase in the gastric volume, free and total acidity and ulcerative index as compared to the control group. The ethanolic extract of seme carpus anacardium at the dose of 400 mg/kg showed significant reduction in the above parameters which was comparable to the standard drug Ranitidine (50 mg /Kg). Semecarpus anacardium extract showed ulcer protection index 70.45% where as standard drug Ranitidine showed ulcer protection index 76.13%.

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