World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

ISOLATION AND PARTIAL CHARACTERIZATION OF A DIHYDROFLAVONOL FROM SUDANESE ACACIA NILOTICA SUBSP. NILOTICA PODS AND ANTIBACTERIAL ACTIVITY OF POD FRACTIONS

Abel Karim M.*, Shaza A. and Mohamed S.

ABSTRACT

From the methanolic extract of, Acacia nilotica subsp. nilotica a flavonoid - compound I has been isolated. The extract was purified by thin layer chromatography and the isolated flavonoid was partially characterized via some spectroscopic data (UV, 1HNMR). Some fractions of Acacia nilotica were evaluated for antimicrobial potential against Gram negative (Escherichia coli and Pseudomonas aeruginosa); Gram positive (Bacillus subtilis and Staphylococcus aureus) and the fungal species Candida albicans. The ethyl acetate and ethanol fractions showed moderate activity against Pseudomonas aeruginosa, while the n-butanol fraction exhibited a partial activity. The chloroform and ethanol fractions showed partial activity against Staphylococcus aureus.

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