World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF TRICHYSPERMUM AMMI MARKETED IN KHARTOUM (SUDAN)

Abdel Karim M.*, Amna D., Weam A. K. and El-Hafez M.

ABSTRACT

Trichyspermum ammi is a herb of diverse uses in Sudanese ethnomedicine. It is an annual herbaceous plant reaching 30-70cm in height .Fruits are claimed to have antimicrobial, antiseptic and antithelmintic properties. The oil from Trichyspermum ammi was studied by GC-MS. It was also evaluated for antimicrobial activity. The GC-MS analysis showed eleven components. Major constituents are: 9-octadecenoic acid –(Z)- methyl ester(61.11%), 9,12-octadecadienoic acid-(ZZ)-, methyl ester(29.57%) and hexadecanoic acid methyl ester(6.53%). The oil showed significant antibacterial activity against Staphylococcus aureus. It also showed significant anticandidal activity It exhibited partial activity against Pseudomonas aeruginosa.

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